Oregon State University (2009~)


Organic: 38. “On the Formation of Aza-ortho-quinone Methides Under Room Temperature Conditions: Cs2CO3 Effect,” Walden, D. M.; Jaworski, A. A.; Johnston, R. C.; Hovey, M. T.; Baker, H. V.; Meyer, M. P.; Scheidt, K. A.; Cheong, P. H.-Y.
J. Org. Chem. 2017, Accepted. 

Organic: 37. “A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products,” Hovey, M. T.; Cohen, D. T.; Walden, D. M.; Cheong, P. H.-Y.; Scheidt, K. A.
Angew. Chem. Int. Ed. 2017, Accepted.

Inorganic/Materials: 36. "Group additivity-Pourbaix diagrams advocate thermodynamically stable nanoscale clusters in aqueous environments," Wills, L. A.; Qu, X.; Chang, I.-Y.; Mustard, T. J. L.; Keszler, D. A.; Persson, K. A.; Cheong, P. H.-Y.
Nature Comm. 2017, 8, 15852. DOI: 10.1038/ncomms15852

Inorganic/Materials: 35. "Aqueous tantalum polyoxometalate reactivity with peroxide," Fullmer, L. B.; Malmberg, C. E.; Fast, D. B.; Wills, L. A.; Cheong, P. H.-Y.; Dolgos, M. R.; Nyman, M.
Dalton Transactions. 2017, Accepted.

Organic: 34. “Computational and Experimental Evidence of Emergent Equilibrium Isotope Effects in Anion Receptor Complexes” Treska, B. W.; Brueckner, A. C.; Haley, M. M.; Cheong, P. H.-Y.; Johnson, D. W. 
J. Am. Chem. Soc. 2017, 139, 3962–3965. DOI: 10.1021/jacs.7b00612

Organic: 33. “Catalytic Enantioselective [2,3]-Rearrangements of Allylic Ammonium Ylides: A Mechanistic and Computational Study” West, T. H.; Walden, D. M.; Taylor, J. E.; Brueckner, A. C.; Johnston, R. C.; Cheong, P. H.-Y.; Lloyd-Jones, G. C.; Smith, A. D.
J. Am. Chem. Soc. 2017, 139, 4366–4375. DOI: 10.1021/jacs.6b11851

Organic: 32. "Schinortriterpenoids: A Case Study in Synthetic Design," Li, X.; Cheong, P. H.-Y.; Carter, R. G.
Angewandte Chem. Int. Ed.201756, 1704–1718. DOI: 10.1002/anie.201609372


Inorganic/Materials: 31. "Isomerization of Keggin Al13 Ions Followed by Diffusion Rates," Oliveri, A. F.; Colla, C. A.; Perkins, C. K.; Akhavantabib, N.; Callahan, J. R.; Pilgrim, C. D.; Smart, S. E.; Cheong, P. H.-Y.; Pan, L.; Casey, W. H.
Chem. Eur. J., 2016, 22, 18682–18685. DOI: 10.1002/chem.201604640 (VIP Paper)

Organic: 30. "Non-bonding 1,5-S⋯O interactions govern chemo- and enantioselectivity in isothiourea-catalyzed annulations of benzazoles," Robinson, E. R. T.; Walden, D. M.; Fallan, C.; Greenhalgh, M. D.; Cheong, P. H.-Y.; Smith, A. D.
Chem. Sci., 2016, 7, 6919–6927. DOI: 10.1039/C6SC00940A

Organic: 29. "MIDA boronates are hydrolysed fast and slow by two different mechanisms," Gonzalez, J. A.; Ogba, O. M.; Morehouse, G. F.; Rosson, N.; Houk, K. N.; Leach, A. G.; Cheong, P. H.-Y.; Burke, M. D.; Lloyd-Jones, G. C.
Nature Chemistry, 2016, 8, 1067–1075. DOI: 10.1038/nchem.2571

Biology: 28. "Peroxiredoxin Catalysis at Atomic Resolution," Perkins, A.; Parsonage, D.; Nelson, K. J.; Ogba, O. M.; Cheong, P. H.-Y.; Poole, L. B.; Karplus, P. A.
Structure, 2016, 24, 1668–1678. DOI: 10.1016/j.str.2016.07.012

Organic: 27. "Diastereoselective Synthesis of and Mechanistic Understanding for the Formation of 2-Piperidinones from Imines and Cyano-Substituted Anhydrides," Di Maso, M. J.; Snyder, K. M.; Fernandes, F. D. S.; Pattawong, O.; Tan, D. Q.; Fettinger, J. C.; Cheong, P. H.-Y.; Shaw, J. T.
Chem. Eur. J., 2016, 22, 4794–4801. DOI: 10.1002/chem.201504424

Organic: 26. "Towards theory driven structure elucidation of complex natural products: mandelalides and coibamide A," Snyder, K. M.; Sikorska, J.; Ye, T.; Fang, L.; Su, W.; Carter, R. G.; McPhail, K. L.; Cheong, P. H.-Y.
Org. Biomol. Chem., 2016, 14, 5826-5831. DOI: 10.1039/C6OB00707D

Organic: 25. "Construction of Stereogenic α,α-Disubstituted Cycloalkanones via 1° Amine Thiourea Dual Catalysis: Experimental Scope and Computational Analyses," Kang, J. Y.; Johnston, R. C.; Snyder, K. M.; Cheong, P. H.-Y.; Carter, R. G.
J. Org. Chem., 2016, 81, 3629–3637. DOI: 10.1021/acs.joc.6b00280

Organic: 24. "Computational Insights into the Central Role of Nonbonding Interactions in Modern Covalent Organocatalysis," Walden, D. M. W.; Ogba, O. M.; Johnston, R. C.; Cheong, P. H.-Y.
Acc. Chem. Res., 2016, 49, 1279–1291. DOI: 10.1021/acs.accounts.6b00204


Inorganic/Materials23. "An Overview of Selected Current Approaches to the Characterization of Aqueous Inorganic Clusters," Jackson, Jr., M. N.; Kamunde-Devonish, M. K.; Hammann, B. A.; Wills, L. A.; Fullmer, L. B.; Hayes, S. E.; Cheong, P. H.-Y.; Casey, W. H.; Nyman, M. D.; Johnson, D. W.
Dalton Transactions201544, 16982–17006. DOI: 10.1039/C5DT01268F

Inorganic/Materials: 22. "Solution structural characterization of an array of nanoscale aqueous inorganic Ga13xInx (0 > x > 6) clusters by H-NMR and QM computations," Oliveri, A. F.; Wills, L. A.; Hazlett, C. R.; Carnes, M. E.; Chang, I.-Y.; Cheong, P. H.-Y.; Johnson, D. W.
Chem. Sci.2015, 6, 4071–4085. DOI: 10.1039/C5SC00776C (Edge Article)

Organic: 21. "Catalytic Efficiency Is a Function of How Rhodium(I) (5 + 2) Catalysts Accommodate a Conserved Substrate Transition State Geometry: Induced Fit Model for Explaining Transition Metal Catalysis," Mustard, T. J. L.; Wender, P. A.; Cheong, P. H.-Y.
ACS Catalysis20155, 1758–1763. DOI: 10.1021/cs501828e

Organic: 20. "Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application," Cohen, D. T.; Johnston, R. C.; Rosson, N. T.; Cheong, P. H.-Y.; Scheidt, K. A.
Chem. Comm.2015, 15, 2690–2693. DOI: 10.1039/C4CC09308A


Inorganic/Materials: 19. "Solid State 69Ga and 71Ga NMR study of the nanoscale inorganic cluster [Ga133-OH)62-OH)18(H2O)24](NO3)15," Ma, Z. L.; Wentz, K. M.; Hammann, B. A.; Chang, I.-Y.; Kamunde-Devonish, M. K.; Cheong, P. H.-Y.; Johnson, D. W.; Terskikh, V. V.; Hayes, S. E.
Chem. Mater., 2014, 26, 4978–4983. DOI: 10.1021/cm501862u

Organic: 18. "Catalyst selective and regiodivergent O- to C- or N-carboxyl transfer of pyrazolyl carbonates: synthetic and computational studies,"  Gould, E.; Walden, D. M.; Kasten, K.; Johnston, R. C.; Wu, J.; Slawin, A. M. Z.; Mustard, T. J. L.; Johnston, B.; Davies, T.; Cheong, P. H.-Y. and Smith, A. D.
Chem. Sci., 2014, 5, 3651–3658. DOI: 10.1039/C4SC00879K

Organic: 17. "The Nature of Persistent Conformational Chirality, Racemization Mechanisms, and Predictions in Diarylether Heptanoid Cyclophane Natural Products,"  Pattawong, O.; Salih, M. Q.; Rosson, N. T.; Beaudry, C. M.; Cheong, P. H.-Y.
Org. Biomol. Chem. 2014, 12, 3303–3309. DOI: 10.1039/C3OB42550A

Organic: 16. "Catalytic Kinetic Resolution of a Dynamic Racemate: Highly Stereoselective β-Lactone Formation by N-Heterocyclic Carbene Catalysis," Johnston, R. C.; Cohen, D. T.; Eichman, C. C.; Scheidt, K. A.; Cheong, P. H.-Y. 
Chem. Sci. 2014, 5, 1974–1982. DOI: 10.1039/C4SC00317A

Organic: 15. "Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst," Jang, K. P.; Hutson, G. E.; Johnston, R. C.; McCusker, E. O.; Cheong, P. H.-Y.; Scheidt, K. A. 
J. Am. Chem. Soc. 2014136, 76–79. DOI: 10.1021/ja410932t

Environmental: 14. "Novel Nitro-PAH Formation from Heterogeneous Reactions of PAHs with NO2, NO3/N2O5, and OH Radicals: Prediction, Laboratory Studies and Mutagenicity," Jariyasopit, N.; McIntosh, M.; Zimmermann, K.; Arey, J.; Atkinson, R.; Cheong, P. H.-Y.; Carter, R. G.; Yu, T.-W.; Dashwood, R. H.; Simonich, S. L. M. 
Environ. Sci. Technol. 2014, 48, 412–419. DOI: 10.1021/es4043808


Inorganic/Materials: 13. "Electrolytic Synthesis of Aqueous Aluminum Nanoclusters and in situ Characterization by Femtosecond Raman Spectroscopy and Computations," Wang, W.; Liu, W.; Chang, I.-Y.; Wills, L. A.; Zakharov , L. N.; Boettcher , S. W.; Cheong, P. H.-Y.; Fang, C.; Keszler, D. A.
Proc. Natl. Acad. Sci. USA 2013, 110, 18397–18401. DOI: 10.1073/pnas.1315396110

Organic: 12. "Palladium-Catalyzed Completely Linear-Selective Negishi Cross-Coupling of Allylzinc Halides with Aryl and Vinyl Halides," Yang, Y.; Mustard, T. J. L.; Cheong, P. H.-Y.; Buchwald, S. L.
Angew. Chem. Int. Ed. 2013, 52, 14098–14102. DOI: 10.1002/anie.201308585

Organic: 11. "Stereocontrol in Asymmetric γ-Lactam Syntheses from Imines and Cyanosuccinic Anhydrides," Pattawong, O.; Tan, D. Q.; Fettinger, J. C.; Shaw, J. T.; Cheong, P. H.-Y.
Org. Lett. 2013, 15, 5130-5133. DOI: 10.1021/ol402561q

Organic: 10. "Stereoselective Synthesis of γ-Lactams from Imines and Cyanosuccinic Anhydrides," Tan, D. Q.; Younai, A.; Pattawong, O.; Fettinger, J. C.; Cheong, P. H.-Y.; Shaw, J. T.
Org. Lett. 2013, 15, 5126–5129. DOI: 10.1021/ol402554n

Inorganic/Materials: 9. "Identifying Nanoscale M13 Clusters in the Solid State and Aqueous Solution: Vibrational Spectroscopy and Theoretical Studies," Jackson, M. N.; Wills, L. A.; Chang, I.-Y.; Carnes, M. E.; Scatena L. F.; Cheong, P. H.-Y.; Johnson, D. W.
Inorg. Chem.
2013, 52, 6187–6192. DOI: 10.1021/ic400611z

Organic: 8. "C-H---O Non-Classial Hydrogen Bonding in the Stereomechanics of Organic Transformations: Theory and Recognition," Johnston, R. C.; Cheong, P. H.-Y.
Org. Biomol. Chem. 2013, 11, 5057–5064. DOI: 10.1039/C3OB40828K

Inorganic/Materials: 7. "[Sc2(µ-OH)2(H2O)6(NO3)2](NO3)2: Aqueous Synthesis and Characterization," Wang, W.; Chang, I-Y.; Zakharov, L.; Cheong, P. H.-Y.; Keszler, D.
Inorg. Chem. 2013, 52, 1807–1811. DOI: 10.1021/ic301814z

Organic: 6. "Mechanism and the Origins of Stereospecificity in Copper-Catalyzed Ring Expansion of Vinyl Oxiranes: A Traceless Dual Transition-Metal-Mediated Process," Mustard, T. J. L.; Mack, D. J.; Njardarson, J. T.; Cheong, P. H.-Y.
J. Am. Chem. Soc. 2013, 135, 1471–1475. DOI: 10.1021/ja310065z

Organic: 5. "Mechanism and Stereocontrol: Enantioselective Addition of Pyrrole to Ketenes using Planar-Chiral Organocatalysts," Pattawong, O.; Mustard, T. J. L.; Johnston, R. C.; Cheong, P. H.-Y.
Angew. Chem. Int. Ed. 2013, 52, 1420–1423. DOI: 10.1002/anie.201208417


Organic: 4. "Synthesis and Computational Analysis of Densely Functionalized Triazoles Using o-Nitrophenylalkynes," McIntosh, M. L.; Johnston, R. C.; Pattawong, O.; Ashburn, B. O.; Naffziger, M. R.; Cheong, P. H.-Y.; Carter, R. G.
J. Org. Chem. 2012, 77, 1101–1112. DOI: 10.1021/jo202467k

Organic: 3. "Organocatalytic Kinetic Resolution Cascade Reactions: New Mechanistic and Stereochemical Manifold in Diphenyl Prolinol Silyl Ether Catalysis," McGarraugh, P. G.; Johnston, R. C.; Martínez-Muñoz, A.; Cheong, P. H.-Y.; Brenner-Moyer, S. E.
Chem. Eur. J. 2012, 18, 10742–10752. DOI: 10.1002/chem.201104029

Organic: 2. "Mechanism and Stereoselectivity of a Dual Amino-Catalyzed Robinson Annulation: Rare Duumvirate Stereocontrol," Pierce, M. D.; Johnston, R. C.; Mahapatra, S.; Yang, H.; Carter, R. G.; Cheong, P. H.-Y.
J. Am. Chem. Soc. 2012, 134, 13624–13631. DOI: 10.1021/ja3018219


Organic1. "Highly Stereoselective and Scalable anti-Aldol Reactions Using N-(p-Dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide: Scope and Origins of Stereoselectivities," Yang, H.; Mahapatra, S.; Cheong, P. H.-Y.; Carter, R. G. 
J. Org. Chem. 201075, 7279–7290. DOI: 10.1021/jo1015008


AB (Bowdoin College, ME), PhD, and PostDoc (UCLA)


19. "Quantum Mechanical Investigations of Organocatalysis: Mechanisms, Reactivities, and Selectivities," Cheong, P. H.-Y.; Legault, C. Y.; Um, J. M.; Çelebi-Ölçüm, N.; Houk, K. N.
Chem. Rev. 2011, 111, 5042-137.


18. "Highly Stereoselective and Scalable anti-Aldol Reactions Using N-(p-Dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide: Scope and Origins of Stereoselectivities," Yang, H.; Mahapatra, S.; Cheong, P. H.-Y., Carter, R.
J. Org. Chem. 2010, 75, 7279–7290.

17. "Electronic and Steric Control of Regioselectivities of Rh(I)-Catalyzed (5+2) Cycloadditions of Vinylcyclopropanes and Substituted Alkynes: An Experimental and Computational Study," Liu, P.; Sirois, L. E.; Cheong, P. H.-Y.; Yu, Z.-X.; Hartung, I. V.; Rieck, H.; Wender, P. A.; Houk, K. N.
J. Am. Chem. Soc. 2010, 132, 10127–10135.


16. "The Role of Twist-Mode Asynchronicity in Exo-Selective Bimolecular Diels–Alder Reactions: A Synthetic and Computational Study," Lam, Y.-H.; Cheong, P. H.-Y.; Blasco Mata, J. M.; Stanway, S. J.; Gouverneur, V.; Houk, K. N.
J. Am. Chem. Soc. 2009, 131, 5, 1947–1957.


15. "Origins of Stereoselectivity in the Oxido-Alkylidenation of Alkynes," Canterbury, D. P.; Frontier, A. J.; Um, J. M.; Cheong, Paul H.-Y.; Goldfeld, D. A.; Huhn, R. A.; Houk K. N.
Org. Lett. 2008, 10, 4597-4600.

14. "Computational Prediction of Small Molecule Catalysts," Houk, K. N.; Cheong, P. H.-Y.
Nature 2008, 455, 309-313.

13. "Origins of the Double Asymmetric Induction in Proline-Catalyzed Aldol Reactions," Calderón, F.; Doyagüez, E. G.; Cheong, P. H.-Y.; Fernández-Mayoralas, A.; Houk, K. N.,
J. Org. Chem. 2008, 73, 7916-7920.

12. "Substituent Effects, Reactant Preorganization, and Ligand Exchange Control the Reactivity in Rh1-Catalyzed (5+2) Cycloadditions between Vinylcyclopropanes and Alkynes," Liu, P.; Cheong, P. H.-Y.; Yu, Z. X.; Wender, P. A.; Houk, K. N.
Angew. Chem. Int. Ed. 2008, 47, 3939-3941.

11. "Gold-Catalyzed Cycloisomerization of 1,5-Allenynes via Dual Activation of an Ene Reaction," Cheong, P. H.-Y.; Morganelli, P.; Luzung, M. R.; Houk, K. N.; Toste, F. D.,
J. Am. Chem. Soc. 2008, 130, 4517-4526.

10. "Origins of Differences in Reactivities of Alkenes, Alkynes, and Allenes in [Rh(CO)2Cl]2-Catalyzed (5+2) Cycloaddition Reactions with Vinylcyclopropanes," Yu, Z.-X.; Cheong,P. H.-Y.; Liu, P.; Legault, C. Y.; Wender, P. A.; Houk, K. N.,
J. Am. Chem. Soc. 2008, 130, 2378-2379.

9. "Catalysis of 3-Pyrrolidinecarboxylic Acid and Related Pyrrolidine Derivatives in Enantioselective anti-Mannich-Type Reactions: Importance of the 3-Acid Group on Pyrrolidine for Stereocontrol," Zhang, H.; Mitsumori, S.; Utsumi, N.; Imai, M.; Garcia-Delgado, N.; Mifsud, M.; Albertshofer, K.; Cheong, P. H.-Y.; Houk, K. N.; Tanaka, F.; Barbas III, C. F.,
J. Am. Chem. Soc. 2008, 130, 875-886.


8. "Torsional steering controls the stereoselectivity of epoxidation in the Guanacastepene A synthesis," Cheong, P. H.-Y.; Yun, H.; Danishefsky, S. J.; Houk, K. N.,
Org. Lett. 2006, 8, 1513-1516.

7. "Pipecolic acid-catalyzed direct asymmetric Mannich reactions," Cheong, P. H.-Y.; Zhang, H. L.; Thayumanavan, R.; Tanaka, F.; Houk, K. N.; Barbas, C. F.,
Org. Lett. 2006, 8, 811-814.

6. "Direct asymmetric anti-Mannich-Type reactions catalyzed by a designed amino acid," Mitsumori, S.; Zhang, H.; Cheong, P. H.-Y.; Houk, K. N.; Tanaka, F.; Barbas, C. F.,
J. Am. Chem. Soc. 2006, 128, 1040-1041.


5. "Origins and predictions of stereoselectivity in intramolecular aldol reactions catalyzed by proline derivatives," Cheong, P. H.-Y.; Houk, K. N.,
Synthesis 2005, (9), 1533-1537.


4. "Origins of selectivities in proline-catalyzed alpha-aminoxylations," Cheong, P. H.-Y.; Houk, K. N.,
J. Am. Chem. Soc. 2004, 126, 13912-13913.

3. "Catalysis of the Hajos-Parrish-Eder-Sauer-Wiechert reaction by cis- and trans-4,5-methanoprolines: Sensitivity of proline catalysis to pyrrolidine ring conformation," Cheong, P. H.-Y.; Houk, K. N.; Warrier, J. S.; Hanessian, S.,
Adv. Synth. Cat. 2004, 346, 1111-1115.

2. "Theory of asymmetric organocatalysis of aldol and related reactions: Rationalizations and predictions," Allemann, C.; Gordillo, R.; Clemente, F. R.; Cheong, P. H.-Y.; Houk, K. N.,
Acc. Chem. Res. 2004, 37, 558-569.


1. "Identification of Jahn-Teller effects in both singlet and triplet low-energy states of [(eta(6)-benzene)Nb(CO)(3)](+)," Abu-Hasanayn, F.; Cheong, P. H.-Y.; Oliff, M.,
Angew. Chem. Int. Ed. 2002, 41, 2120-2122.